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Tangshan (Yen Zidan) returns home after learning medical skills from abroad, and sets up a Western medicine clinic with his assistant Liu Guobang in the slum of Zhabei, Shanghai. In order to get a piece of land, Yu Laoqi (Yu Rongguang), a local axe gang bully, often brings people to beat villagers. Tangshan and Liu Guobang stop the murders and treat the injured villagers voluntarily. In order to stop Yu Laoqi, Tangshan visited the owner of the land, Simon, his teacher when he was in England. Considering Simon's work as the price, Tangshan saved the villagers' land. Yu Xiaoqian (Zhu Yin), Yu Laoqi's younger sister, has been suffering from throat disease for many years and can't speak. Yu Laoqi, who believes in fox immortals, thinks that seeking immortals can cure her sister and rejects western medicine. Xiao Qian meets Tangshan by chance. The sincerity of the latter moves Xiao Qian and makes her undergo surgery. At the same time, the children in the slums disappeared one after another. Tangshan found that the behind the scenes were the Axe Gang and Simon. A fierce battle was inevitable